5-Second "Trick"
Rejuvenates
Stiff & Sore Joints
(Seniors Swear By THIS)

Supporting Clinical Studies

• 01.Bakilan, F., Armagan, O., Ozgen, M., Tascioglu, F., Bolluk, O., & Alatas, O. (2016). Effects of Native Type II Collagen Treatment on Knee OA: A Randomized Controlled Trial. The Eurasian Journal of Medicine, 48(2), 95–101.
• 02.Di, L., Mannelli, C., Maresca, M., Micheli, L., Martinez-puig, D., & Ghelardini, C. (n.d.). LOW DOSE CHICKEN NATIVE TYPE II COLLAGEN Inflammatory infiltrate. Florence, Italy.
• 03.Scarpellini, M., Lurati, A., Vignati, G., Marrazza, M. G., Telese, F., Re, K., & Bellistri, A. (2008). Biomarkers, type II collagen, glucosamine and chondroitin sulfate in OA follow-up: The "Magenta OA study." Journal of Orthopaedics and Traumatology, 9(2), 81–87.
• 04.Douglas S Kalman, Maria Heimer, Anita Valdeon, Howard Schwartz and Eric Sheldon. Effect of a natural extract of chicken combs with a high content of hyaluronic acid on pain relief and quality of life in subjects with knee OA: a pilot randomized double-blind placebo-controlled trial. Nutrition Journal 2008;7(3):1-9.
• 05.Möller I, Martinez-Puig D, Chetrit C. Oral administration of a natural extract rich in hyaluronic acid for the treatment of knee OA with synovitis: a retrospective cohort study. Clinical Nutrition Supplements 2009;4(2):171-172..
• 06.Martinez-Puig D, Möller I, Fernández C, Chetrit C. Efficacy of oral administration of yoghurt supplemented with a preparation containing hyaluronic acid (MobileeTM) in adults with mild joint discomfort: a randomized, double-blind, placebo controlled intervention study. Mediterranean Journal of Nutrition and Metabolism
  2013;6:63–68.

• 07.Sánchez J, Bonet ML, Keijer J, van Schothorst EM, Mölller I, Chetrit C, Martinez-Puig D, Palou A. Blood cells transcriptomics as source of potential biomarkers of articular health improvement: effects of oral intake of a rooster combs extract rich in hyaluronic acid. Genes & Nutrition 2014; 9: 417.
• 08.Moriña D, Solà R, Valls RM, López de Frutos V, Montero M, Giralt M, Papell I, Bernal G, Faba J, Casajuana C, Rodríguez A, Chetrit C, Martinez-Puig, D. Efficacy of a Low-fat Yogurt Supplemented with a Rooster Comb Extract on Joint Function in Mild Knee Pain Patients: A Subject-level Meta-analysis. Annals of Nutrition and Metabolism 2013;63(S1):1386.
• 09.Int J Med Sci. 2010 Nov 1;7(6):366-77, Comparative Efficacy and Tolerability of 5-Loxin and Aflapin Against OA of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study.
• 10.IToxicol Mech Methods. 2010 Nov;20(9):556-63, Epub 2010 Sep 29. Safety and toxicological evaluation of Aflapin®: A novel Boswellia-derived anti-inflammatory product.
• 11.Int J Med Sci. 2011 Oct 12;8(7):615-622, A Double Blind, Randomized, Placebo Controlled Clinical Study Evaluates the Early Efficacy of Aflapin® in Subjects with OA of Knee.